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VERSION:2.0
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CALSCALE:GREGORIAN
X-WR-CALNAME:EHS Seminar | Dr. Ulrike Dydak: Advanced Neuroimaging to study
  the risk of Manganese Toxicity in Welders
X-WR-TIMEZONE:Eastern Time (US & Canada)
BEGIN:VEVENT
DTSTAMP:20260904T165620Z
UID:tag:localist.com\,2008:EventInstance_51782815017920
DTSTART:20260122T163000Z
DTEND:20260122T180000Z
DESCRIPTION:Dr. Dydak is Director of the Purdue-IU Medical Physics Program 
 and Associate Director\nof the Women’s Global Health Institute at Purdue
  University. With a background in\nmedical physics\, her NIH-supported res
 earch is focused on the development of novel\nmagnetic resonance imaging (
 MRI) and spectroscopy (MRS) techniques and their\ntranslation to clinical 
 and life science studies. Dr. Dydak pioneered the use of\nquantitative MRI
  (qMRI) and edited MRS techniques to determine the effect of\nexposure to 
 welding fumes on the dynamics of brain manganese deposition and on\naltera
 tions in neurochemicals\, such as the inhibitory neurotransmitter gamma am
 ino\nbutyric acid (GABA).\nShe reported on increased brain Mn levels corre
 lating with cognitive outcomes\, on\nnovel MRI ways to assess excess manga
 nese on a whole-brain basis\, as well as on\nsignificantly elevated in viv
 o levels of the neurotransmitter gamma-aminobutyric acid\n(GABA). In some 
 brain regions those changes were reversible\, with the rate of change\nbei
 ng modulated by the amount of life-long exposure to Mn.\nCurrent studies u
 se novel quantitative MRI (qMRI) and advanced MRS editing\ntechniques to e
 xplore the dose-response relationships of uptake and elimination of Mn\nan
 d other heavy metals into specific brain regions of the human brain\, the 
 metal burden\nof the individual brain for risk assessment\, and the relati
 onship of brain Mn to oxidative\nstress markers\, neurotransmitter imbalan
 ces and neurological outcomes.
LOCATION:FIU MMC\, AHC5-300
SUMMARY:EHS Seminar | Dr. Ulrike Dydak: Advanced Neuroimaging to study the 
 risk of Manganese Toxicity in Welders
URL;VALUE=URI:https://calendar.fiu.edu/event/ehs-seminar-dr-ulrike-dydak-ad
 vanced-neuroimaging-to-study-the-risk-of-manganese-toxicity-in-welders
CATEGORIES:Lectures & Conferences
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