Flies to the Rescue: Mechanisms and Therapeutics for Rare Diseases
This is a past event.
Friday, March 12, 2021 at 11:00am to 12:00pmVirtual Event
Join us for a talk on "Flies to the Rescue: Mechanisms and Therapeutics for Rare Diseases” with Dr. R. Grace Zhai, Professor, Department of Molecular and Cellular Pharmacology, Senior Associate Dean for Basic Science Research, University of Miami Miller School of Medicine.
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Dr. Zhai’s research is focused on understanding the genetic and molecular mechanisms of neural degeneration and protection in the context of both common and rare neurological disorders. Her group uses ‘Drosophila - mammalian two-model’ systems, to identify genetic components in Drosophila and characterize the cellular mechanisms in mammalian cells. Her group discovered and characterized one of the most robust neuroprotective factors that has broad therapeutic potential against several neurodegenerative diseases including Alzheimer’s and Huntington’s disease. At the same time, her group has established numerous genetic models for rare diseases and carried out mechanistic analysis of neurological phenotypes that have led to successful therapies in human patients. In this seminar, she will discuss their recent work on the pathological mechanisms underlying metabolic disorders that has led to therapies for these rare diseases.